Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 10/20 | 0.32 |
| ▸ | PPARG | P37231 | 10/20 | 0.32 |
| ▸ | PPARD | Q03181 | 10/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730831 | 0.94 | FFAR4 (0.39) | FFAR4PTGS1PPARAPPARGPPARD | |
| SCHEMBL10735559 | 0.85 | FFAR4 (0.35) | FFAR4PTGS1PPARAPPARGPPARD | |
| SCHEMBL10661817 | 0.85 | FFAR4 (0.41) | FFAR4PTGS1PPARAPPARGPPARD | |
| SCHEMBL10658344 | 0.84 | PTGS1 (0.42) | PTGS1KDM4EGPBAR1NPC1CA12 | |
| SCHEMBL10733392 | 0.83 | FFAR4 (0.39) | FFAR4PTGS1KDM4EPPARAPPARG | |
| Hydrochloric Acid SCHEMBL10729202 | 0.82 | TP53 (0.39) | FFAR4PTGS1KDM4EPPARAPPARG | |
| SCHEMBL10734793 | 0.82 | FFAR4 (0.34) | FFAR4PPARAPPARGPPARDNPC1 | |
| SCHEMBL10735554 | 0.81 | NPC1 (0.35) | PTGS1KDM4EPPARAPPARGPPARD | |
| SCHEMBL10730760 | 0.81 | HTR1A (0.35) | FFAR4GABRA5 | |
| SCHEMBL10729865 | 0.81 | FFAR4 (0.35) | FFAR4GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4644064-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-02-17 | — | — | US | disclosed |