Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 11/20 | 0.36 |
| ▸ | PPARG | P37231 | 11/20 | 0.36 |
| ▸ | PPARD | Q03181 | 11/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733392 | 0.89 | FFAR4 (0.39) | FFAR4ALOX5APFEN1PPARAPPARG | |
| Hydrochloric Acid SCHEMBL10729202 | 0.88 | TP53 (0.39) | FFAR4ALOX5APFEN1PPARAPPARG | |
| SCHEMBL10730831 | 0.88 | FFAR4 (0.39) | FFAR4PPARAPPARGPPARDPTGS1 | |
| SCHEMBL10664951 | 0.86 | ALOX5AP (0.37) | ALOX5APFEN1PPARAPPARGPPARD | |
| SCHEMBL10730283 | 0.85 | FFAR4 (0.39) | FFAR4PPARAPPARGPPARDPTGS1 | |
| SCHEMBL10657284 | 0.84 | FFAR4 (0.40) | FFAR4PPARAPPARGPPARDPTGS1 | |
| SCHEMBL4035353 | 0.84 | FFAR4 (0.44) | FFAR4ALOX5APFEN1PPARAPPARG | |
| SCHEMBL10728790 | 0.83 | HPGD (0.43) | FFAR4NPC1 | |
| SCHEMBL10661727 | 0.83 | CASP1 (0.44) | FFAR4PPARAPPARGPPARDPTGS1 | |
| SCHEMBL10733440 | 0.82 | RAB9A (0.45) | FFAR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |
| EP-0002666-B1 | 1,2-BENZISOXAZOLYLOXY (OR THIO) ACETIC ACIDS AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-17 | — | — | EP | disclosed |