Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 10/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732490 | 0.90 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10726821 | 0.89 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10727874 | 0.89 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10726572 | 0.88 | HTT (0.65) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10726195 | 0.87 | LMNA (0.80) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL1672017 | 0.87 | HTT (1.00) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL27954071 | 0.86 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10729946 | 0.85 | HTT (0.68) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| Methyl Alcohol SCHEMBL28334259 | 0.85 | ALDH1A1 (0.98) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL10732027 | 0.84 | HTT (0.67) | ALDH1A1SMN1; SMN2MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680402-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1987-07-14 | — | — | US | disclosed |