Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346356 | 0.92 | ALDH1A1 (0.43) | ALDH1A1GAAHTR1ASLC6A4GFER | |
| SCHEMBL10732172 | 0.90 | GRM5 (0.46) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL30523629 | 0.84 | KMT2A (0.47) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL1344385 | 0.84 | AKR1B1 (0.44) | ALDH1A1HPGDNPSR1 | |
| SCHEMBL20766367 | 0.84 | KMT2A (0.47) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL30730257 | 0.83 | CTNNB1 (0.47) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL10593445 | 0.82 | GRM5 (0.54) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL31409466 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL11476808 | 0.79 | MAOA (0.50) | ALDH1A1GAAGFERSMN1; SMN2CYP4F2 | |
| SCHEMBL19926744 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1GAAGFERSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4701466-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTICOAGULANTS | SYNTHELABO (FR) | 1987-10-20 | — | — | US | disclosed |