Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733811 | 0.82 | EGFR (0.57) | EGFRSMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL3190597 | 0.71 | EGFR (0.50) | EGFRSMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL399816 | 0.70 | EGFR (0.43) | EGFRSMN1; SMN2MAPTALDH1A1CYP1A2 | |
| SCHEMBL3199606 | 0.69 | EGFR (0.51) | EGFRSMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL3812007 | 0.69 | ALDH1A1 (0.39) | SMN1; SMN2MAPTHPGDNPC1TP53 | |
| SCHEMBL3809831 | 0.69 | KMT2A (0.39) | EGFRSMN1; SMN2MAPTTSHRNPC1 | |
| SCHEMBL22528250 | 0.68 | SMN1; SMN2 (0.47) | EGFRSMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL12925954 | 0.68 | EGFR (0.47) | EGFRSMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL14603345 | 0.68 | TNKS (0.45) | MAPTHPGDTSHRALDH1A1CYP1A2 | |
| SCHEMBL13576829 | 0.68 | KDM4E (0.53) | EGFRSMN1; SMN2MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707476-A | TRANQUILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |