SCHEMBL1073248

SCHEMBL1073248

COc1ccccc1C(=O)OCC(C)C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.74
TSHR P16473 1/20 0.74
KMT2A Q03164 3/20 0.58
MAPT P10636 2/20 0.58
ATM Q13315 2/20 0.58
MEN1 O00255 2/20 0.58
TP53 P04637 2/20 0.58
NPY1R P25929 1/20 0.58
NPY2R P49146 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HPGD P15428 3/20 0.54
HTT P42858 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
XBP1 P17861 1/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CTSD P07339 1/20 0.51
HSD17B10 Q99714 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020498 0.87 ALDH1A1 (0.74) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL42787 0.86 ALDH1A1 (1.00) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL8144263 0.86 ALDH1A1 (1.00) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL29387332 0.86 ALDH1A1 (1.00) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL1283916 0.85 ALDH1A1 (0.72) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL5664668 0.85 ALDH1A1 (0.53) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL2612512 0.85 ALDH1A1 (0.53) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL28020067 0.85 ALDH1A1 (0.72) ALDH1A1TSHRKMT2AMAPTATM
Ammonia Solution, Strong SCHEMBL28046886 0.84 ALDH1A1 (0.96) ALDH1A1TSHRKMT2AMAPTATM
SCHEMBL27345462 0.84 ALDH1A1 (0.96) ALDH1A1TSHRKMT2AMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738736-B2 Combined internal donor system for Ziegler-Natta polyolefin catalysts and methods of making and using same W. R. GRACE & CO.-CONN (US) 2017-08-22 US claimed
WO-2016025194-A1 COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME BASF CORPORATION (US) 2016-02-18 WO claimed
US-20160046740-A1 COMBINED INTERNAL DONOR SYSTEM FOR ZIEGLER-NATTA POLYOLEFIN CATALYSTS AND METHODS OF MAKING AND USING SAME W. R. GRACE & CO.-CONN. 2016-02-18 US claimed
CN-122037370-A Conductive polypropylene composition, and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-117924555-A Catalyst component, catalyst system, application of catalyst system and olefin polymerization method 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-117924556-A Spherical magnesium halide adduct and preparation method and application thereof 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-107033263-B Catalytic system for preparing wide-distribution polyolefin and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-105622423-B A kind of adduct of magnesium halides and its preparation method and application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-105622793-B For the catalytic component and catalyst system of olefinic polymerization and its application and olefine polymerizing process 中国石油化工股份有限公司 2019-05-31 CN disclosed
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-03-26 US disclosed
CN-105541877-B Adduct of magnesium halides and application and the catalytic component for olefinic polymerization and catalyst system and application and olefine polymerizing process 中国石油化工股份有限公司 2019-03-22 CN disclosed
CN-101486722-B Magnesium halide adduct, preparation and use thereof CHINA PETROLEUM & CHEMICAL 2011-05-04 CN disclosed
EP-2287208-A1 A catalyst component for olefin polymerization and a catalyst comprising the same China Petroleum & Chemical Corporation (CN) 2011-02-23 EP disclosed
US-20110040051-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND A CATALYST COMPRISING THE SAME BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-17 US disclosed
WO-2011006278-A1 SPHERICAL MAGNESIUM HALIDE ADDUCT, CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION PREPARED THEREFROM CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-01-20 WO disclosed
CN-101486776-B Catalyst component for olefinic polymerization , and catalyst thereof CHINA PETROLEUM & CHEMICAL 2010-12-22 CN disclosed
CN-101486722-A Magnesium halide adduct, preparation and use thereof CHINA PETROCHEMICAL CO LTD (CN) 2009-07-22 CN disclosed
CN-101486776-A Catalyst component for olefinic polymerization , and catalyst thereof CHINA PETROCHEMICAL CO LTD (CN) 2009-07-22 CN disclosed
CN-1318457-C Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2007-05-30 CN disclosed
CN-1743347-A Catalyst component for olefinic polymerization and its catalyst CHINA PETROCHEMICAL CORP (CN) 2006-03-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom MSMO1, SCO2, RTF1 ALDH1A1 3333/4885TSHR 2084/4885KMT2A 2878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.