Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732034 | 0.91 | BCHE (0.35) | KCNH2BCHE | |
| SCHEMBL10735208 | 0.89 | BCHE (0.35) | KCNH2BCHE | |
| SCHEMBL10727561 | 0.79 | BCHE (0.35) | KCNH2BCHE | |
| SCHEMBL10729347 | 0.79 | CHRNA7 (0.37) | — | |
| SCHEMBL10730683 | 0.77 | BCHE (0.36) | BCHE | |
| SCHEMBL10730647 | 0.76 | PPARG (0.39) | BCHE | |
| SCHEMBL11795334 | 0.76 | KCNH2 (0.39) | KCNH2BCHE | |
| SCHEMBL10729081 | 0.75 | RAB9A (0.48) | BCHE | |
| SCHEMBL10729428 | 0.74 | BCHE (0.35) | BCHE | |
| SCHEMBL11291915 | 0.74 | BCHE (0.39) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692464-A | Novel prostacyclin derivatives and a process for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |