Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727476 | 0.81 | HTT (0.30) | — | |
| SCHEMBL10732034 | 0.80 | BCHE (0.35) | — | |
| SCHEMBL10735208 | 0.79 | BCHE (0.35) | — | |
| SCHEMBL10732529 | 0.79 | KCNH2 (0.36) | — | |
| SCHEMBL10729081 | 0.79 | RAB9A (0.48) | — | |
| SCHEMBL9687625 | 0.78 | GAA (0.37) | — | |
| SCHEMBL10734682 | 0.76 | BCHE (0.35) | CHRNA7 | |
| SCHEMBL10727269 | 0.73 | RAB9A (0.34) | — | |
| SCHEMBL10734643 | 0.73 | RAB9A (0.34) | — | |
| SCHEMBL3827791 | 0.71 | RAB9A (0.55) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692464-A | Novel prostacyclin derivatives and a process for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| US-4359581-A | Process for the production of caracyclin intermediates | SCHERING AG (DE) | 1982-11-16 | — | — | US | disclosed |