Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073285 | 1.00 | PKM (0.42) | PKMALDH1A1LMNAGAAVDR | |
| SCHEMBL1019652 | 0.85 | PKM (0.41) | PKMALDH1A1LMNAGAAVDR | |
| SCHEMBL3149448 | 0.81 | ALDH1A1 (0.51) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL3154963 | 0.81 | ALDH1A1 (0.51) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL3149456 | 0.81 | ALDH1A1 (0.51) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL3154839 | 0.80 | PKM (0.44) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL3144836 | 0.80 | PKM (0.44) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL3144829 | 0.80 | PKM (0.44) | PKMALDH1A1LMNAGAAGLA | |
| SCHEMBL568467 | 0.79 | ALDH1A1 (0.49) | ALDH1A1VDRTSHRGLAMEN1 | |
| SCHEMBL567908 | 0.79 | ALDH1A1 (0.49) | ALDH1A1VDRTSHRGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271634-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009133107-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2009-11-05 | — | — | WO | disclosed |