Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733195 | 1.00 | FDPS (0.58) | FDPSMAOBTNFRSF1AALOX5ACHE | |
| SCHEMBL10738830 | 0.92 | FDPS (0.49) | FDPSMAOBTNFRSF1AALOX5ACHE | |
| SCHEMBL10738840 | 0.92 | FDPS (0.49) | FDPSMAOBTNFRSF1AALOX5ACHE | |
| SCHEMBL2744009 | 0.86 | TNFRSF1A (0.60) | TNFRSF1AALOX5KDM4EALDH1A1LMNA | |
| SCHEMBL10737039 | 0.85 | KDM4E (0.62) | TNFRSF1AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10737031 | 0.85 | KDM4E (0.62) | TNFRSF1AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL16562710 | 0.83 | FDPS (0.63) | FDPSMAOBTNFRSF1AALOX5ACHE | |
| SCHEMBL8772845 | 0.82 | MAOB (0.68) | FDPSMAOBALOX5KDM4EALDH1A1 | |
| SCHEMBL8772838 | 0.82 | MAOB (0.68) | FDPSMAOBALOX5KDM4EALDH1A1 | |
| SCHEMBL8772809 | 0.81 | FDPS (0.60) | FDPSMAOBALOX5ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673684-A | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |