Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | FDPS | P14324 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.57 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772838 | 1.00 | MAOB (0.68) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL10732926 | 0.90 | ABCB1 (0.58) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL10732918 | 0.90 | ABCB1 (0.58) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL2394280 | 0.88 | ALOX5 (0.78) | MAOBFDPSALOX5METPKM | |
| SCHEMBL5180134 | 0.88 | ALOX5 (0.78) | MAOBFDPSALOX5METPKM | |
| SCHEMBL8772825 | 0.87 | FDPS (0.61) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL8772828 | 0.87 | FDPS (0.61) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL6986048 | 0.87 | MAOB (0.56) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL3492139 | 0.87 | MAOB (0.56) | MAOBFDPSKDM4EALDH1A1HPGD | |
| SCHEMBL6556432 | 0.86 | MAOB (0.66) | MAOBFDPSALOX5CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016898-B | 3,4-disubstituted pyrroles compounds and its preparation method and application | 上海交通大学 | 2016-07-06 | — | — | CN | disclosed |
| EP-0801071-A1 | LEWIS X DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |