Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460191 | 0.86 | HRH3 (0.46) | HRH3CYP1A2LMNATHRBBLM | |
| SCHEMBL16450380 | 0.77 | KDM4E (0.40) | CYP1A2LMNATHRBBLMCREBBP | |
| SCHEMBL469846 | 0.74 | MAPT (0.35) | HRH3CHRM2LMNABLMCA1 | |
| SCHEMBL14441522 | 0.73 | DNM1 (0.50) | THRBCA1CA2CA9CA12 | |
| SCHEMBL14441520 | 0.73 | DNM1 (0.50) | THRBCA1CA2CA9CA12 | |
| SCHEMBL14441524 | 0.73 | DNM1 (0.50) | THRBCA1CA2CA9CA12 | |
| SCHEMBL4151814 | 0.70 | LMNA (0.65) | CYP1A2LMNATHRBBLMCREBBP | |
| SCHEMBL16136668 | 0.70 | HRH3 (0.43) | HRH3CHRM2NOS1NOS2TDP1 | |
| SCHEMBL428397 | 0.70 | MAPT (0.42) | CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL14869442 | 0.69 | LMNA (0.41) | CYP1A2LMNATHRBBLMCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642344-A | Polyamines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-10 | — | — | US | disclosed |