SCHEMBL10733944

SCHEMBL10733944

CC(C)c1cccc(OC(F)F)c1N(Cn1cccn1)C(=O)CCl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.37
KAT7 O95251 1/20 0.35
KAT6B Q8WYB5 1/20 0.35
KAT6A Q92794 1/20 0.35
THRB P10828 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 2/20 0.34
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 2/20 0.32
NLRP3 Q96P20 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
NR1I2 O75469 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KLKB1 P03952 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
HCRTR1 O43613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10732053 0.88 TP53 (0.45) PDE4BKAT7KAT6BKAT6ATHRB
SCHEMBL10736554 0.88 TP53 (0.42) PDE4BKAT7KAT6BKAT6ATHRB
SCHEMBL10736997 0.77 TP53 (0.42) THRBLMNATP53MEN1KMT2A
SCHEMBL10731615 0.76 TP53 (0.46) PDE4BKAT7KAT6BKAT6ATHRB
SCHEMBL10732595 0.76 TP53 (0.42) THRBLMNATP53MEN1KMT2A
SCHEMBL10729630 0.76 TP53 (0.40) KAT7KAT6BKAT6ATHRBLMNA
SCHEMBL10733949 0.75 MEN1 (0.35) TP53MEN1KMT2ATSHRRAB9A
SCHEMBL9367287 0.75 TP53 (0.56) THRBLMNATP53MEN1KMT2A
Metazachlor SCHEMBL4896537 0.75 TP53 (0.48) THRBTP53MEN1KMT2ATSHR
Metazachlor SCHEMBL55016 0.75 TP53 (0.48) THRBTP53MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4659365-A Herbicidal 2-chloro-2'-fluoroalkoxyacetanilides MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-04-21 US disclosed