SCHEMBL9367287

SCHEMBL9367287

CCc1cccc(CC)c1N(Cn1cccn1)C(=O)CCl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.56
NR1I2 O75469 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
THRB P10828 3/20 0.37
LMNA P02545 1/20 0.37
HDAC1 Q13547 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HTT P42858 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
PAX8 Q06710 2/20 0.35
JAK2 O60674 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433228 0.93 TP53 (0.59) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL8530433 0.89 TP53 (0.44) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL8460980 0.87 TP53 (0.43) TP53NR1I2TDP1MEN1KMT2A
Metazachlor SCHEMBL4896537 0.87 TP53 (0.48) TP53NR1I2TDP1MEN1KMT2A
Metazachlor SCHEMBL55016 0.87 TP53 (0.48) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL10733657 0.86 TP53 (0.45) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL10732053 0.86 TP53 (0.45) TP53NR1I2TDP1MEN1KMT2A
Metazachlor SCHEMBL9576104 0.85 TP53 (0.72) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL10732674 0.85 TP53 (0.44) TP53NR1I2TDP1MEN1KMT2A
SCHEMBL10730497 0.84 TP53 (0.43) TP53NR1I2TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4437876-A PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1984-03-20 US claimed
US-4437875-A PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1984-03-20 US claimed
EP-0094349-B1 Use of quinoline derivatives for the protection of cultivated plants CIBA GEIGY AG (CH) 1994-04-06 EP disclosed
EP-0310555-B1 DERIVATIVES OF 1,5-DIPHENYL-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID FOR CROP PROTECTION AGAINST THE PHYTOTOXIC ACTIVITY OF HERBICIDES CIBA-GEIGY AG (CH) 1993-02-10 EP disclosed
US-5102445-A Plant safening agent CIBA-GEIGY CORPORATION (US) 1992-04-07 US disclosed
US-5077413-A Preferential herbicides CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5045107-A From herbicides, plant safening agents CIBA-GEIGY CORPORATION (US) 1991-09-03 US disclosed
US-5023333-A Derivatives of 8-hydroxyquinoline CIBA-GEIGY CORPORATION (US) 1991-06-11 US disclosed
US-4995899-A Optically active diazabicycloalkane derivatives and their use for protecting crops from the phytotoxic effect of herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
EP-0138773-B1 USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
US-4902340-A Use of quinoline derivatives for the protection of cultivated plants from herbicides CIBA-GEIGY CORPORATION (US) 1990-02-20 US disclosed
EP-0031042-A1 N-Dichloroacetyldiazabicyclo derivatives, process for their preparation, herbicides containing acetanilides as herbicidal agents and these N-dichloroacetyldiazabicyclo derivatives as antidotes and their use to combat undesired plant growth BASF Aktiengesellschaft (DE) 1981-07-01 EP disclosed
US-4272282-A ANTIDOTES BASF AKTIENGESELLSCHAFT (DE) 1981-06-09 US disclosed
EP-0007588-B1 TETRAHYDRO-1,3-OXAZINES, HERBICIDAL COMPOSITIONS CONTAINING ACETANILIDES AS HERBICIDAL AGENTS AND SAID TETRAHYDRO-1,3-OXAZINES AS ANTAGONISTIC AGENTS, AND THEIR USE FOR COMBATING UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
US-4249935-A Herbicidal agents BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
EP-0019171-A1 Herbicidal agent on the basis of N-azolyl-methyl-halogenacetanilides and cyclohexane-1,3-dione derivatives, and its use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-11-26 EP disclosed
EP-0009091-A1 Process for selectively combating undesired plant growth with herbicidal agents comprising acetanilides and N-dichloroacetyl-2,2-dimethyl-1,3-oxazolidine BASF Aktiengesellschaft (DE) 1980-04-02 EP disclosed
EP-0008649-A1 Herbicidal agents comprising acetanilides and N-isopropyl-N-propargyl-dichloracetamide and process for selectively combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-03-19 EP disclosed
EP-0007575-A1 Herbicidal compositions based on acetanilides and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed
EP-0007588-A1 Tetrahydro-1,3-oxazines, herbicidal compositions containing acetanilides as herbicidal agents and said tetrahydro-1,3-oxazines as antagonistic agents, and their use for combating undesired plant growth BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed