Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727269 | 1.00 | RAB9A (0.34) | RAB9AKDM4ENPC1SMN1; SMN2ABCB1 | |
| SCHEMBL9687625 | 0.81 | GAA (0.37) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10729081 | 0.80 | RAB9A (0.48) | RAB9AKDM4ENPC1SMN1; SMN2ABCB1 | |
| SCHEMBL10733946 | 0.79 | BCHE (0.39) | RAB9AKDM4ENPC1SMN1; SMN2ABCB1 | |
| SCHEMBL10734682 | 0.79 | BCHE (0.35) | RAB9AKDM4ENPC1SMN1; SMN2BCHE | |
| SCHEMBL11291915 | 0.78 | BCHE (0.39) | RAB9AKDM4ENPC1SMN1; SMN2ABCB1 | |
| SCHEMBL10730683 | 0.76 | BCHE (0.36) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10727561 | 0.76 | BCHE (0.35) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10729428 | 0.76 | BCHE (0.35) | ABCB1BCHECHRM2CHRM4CHRM1 | |
| SCHEMBL10728743 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692464-A | Novel prostacyclin derivatives and a process for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| US-4359581-A | Process for the production of caracyclin intermediates | SCHERING AG (DE) | 1982-11-16 | — | — | US | disclosed |