Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072779 | 0.89 | GAA (0.39) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16077039 | 0.89 | GAA (0.39) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10729081 | 0.85 | RAB9A (0.48) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10734643 | 0.81 | RAB9A (0.34) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10727269 | 0.81 | RAB9A (0.34) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11291915 | 0.80 | BCHE (0.39) | BCHE | |
| SCHEMBL10733946 | 0.79 | BCHE (0.39) | BCHE | |
| SCHEMBL10729347 | 0.78 | CHRNA7 (0.37) | — | |
| SCHEMBL9732110 | 0.78 | ABCB1 (0.31) | — | |
| SCHEMBL9732106 | 0.78 | ABCB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157042-A | 3-OXA-5-FLUORO-CARBACYCLINS, THEIR PREPARATION AND USE AS MEDICINAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| US-5124343-A | Carbacyclins, process for the preparation thereof, and use thereof as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |
| US-4954524-A | Carbacylcins, their preparation and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |
| US-4708963-A | Novel carbacyclins, their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
| US-4692464-A | Novel prostacyclin derivatives and a process for the preparation thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| US-4497830-A | Carbacyclins, their preparation and pharmacological use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-02-05 | — | — | US | disclosed |
| US-4423067-A | Carbacyclins, their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| US-4359581-A | Process for the production of caracyclin intermediates | SCHERING AG (DE) | 1982-11-16 | — | — | US | disclosed |