Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640730 | 0.85 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| SCHEMBL1195318 | 0.85 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| SCHEMBL8605798 | 0.85 | CYP1A2 (0.64) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| Metaxon SCHEMBL117877 | 0.85 | TDP1 (0.70) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| Metaxon SCHEMBL3533162 | 0.83 | TDP1 (0.68) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| Metaxon SCHEMBL28800416 | 0.83 | TDP1 (0.68) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| Metaxon SCHEMBL27616565 | 0.83 | TDP1 (0.68) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| SCHEMBL11872902 | 0.83 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| SCHEMBL1831224 | 0.83 | CYP1A2 (0.62) | MEN1KMT2ACYP1A2CYP2C9HIF1A | |
| Metaxon SCHEMBL27765431 | 0.83 | TDP1 (0.68) | MEN1KMT2ACYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708733-A | Herbicidal 4-chloro-aryloxy-acetyl- and 4-chloro-aryloxy-propionyl-malonates | BUDAPESTI VEGYIMUVEK (HU) | 1987-11-24 | — | — | US | disclosed |