Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metaxon SCHEMBL117877 | 0.86 | TDP1 (0.70) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| SCHEMBL11640730 | 0.86 | CYP1A2 (0.64) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| SCHEMBL8605798 | 0.86 | CYP1A2 (0.64) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| SCHEMBL1831224 | 0.85 | CYP1A2 (0.62) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| Metaxon SCHEMBL27616565 | 0.85 | TDP1 (0.68) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| SCHEMBL10734762 | 0.85 | MEN1 (0.63) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| Metaxon SCHEMBL3533162 | 0.85 | TDP1 (0.68) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| SCHEMBL11872902 | 0.85 | MEN1 (0.68) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| Metaxon SCHEMBL28800416 | 0.85 | TDP1 (0.68) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 | |
| Metaxon SCHEMBL27765431 | 0.85 | TDP1 (0.68) | CYP1A2CYP2C9HIF1ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400568-B | 7-aryloxy acetoxyl isoflavone derivative and application thereof in pesticides | 江苏大学 | 2022-10-25 | — | — | CN | claimed |
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-12-19 | — | — | US | disclosed |
| US-12116351-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-10-15 | — | — | US | disclosed |
| US-20220380322-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2022-12-01 | — | — | US | disclosed |
| CN-109400568-B | 7-aryloxy acetoxyl isoflavone derivative and application thereof in pesticides | 江苏大学 | 2022-10-25 | — | — | CN | disclosed |
| US-11434207-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2022-09-06 | — | — | US | disclosed |
| CN-110041198-B | Synthesis method of chalcone-containing aryloxycarboxylate compound and application of the compound in pesticide | 江苏大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | disclosed |
| US-20200223806-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2020-07-16 | — | — | US | disclosed |
| CN-111333588-A | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-06-26 | — | — | CN | disclosed |
| EP-0593998-A1 | Pyrimidinylthioalkane herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0207690-B1 | N-SUBSTITUTED GLUTAMIC ACID DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF | SUNTORY LIMITED (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4701210-A | HERBICIDES | SUNTORY LIMITED (JP) | 1987-10-20 | — | — | US | disclosed |
| EP-0090312-B1 | 3-ACYL SUBSTITUTED DERIVATIVES OF 2- OR 4-THIAZOLIDINE-CARBOXYLIC ACID HAVING A PHYTO GROWTH REGULATING AND BIOSTIMULATING ACTION | Montedison S.p.A. (IT) | 1987-09-09 | — | — | EP | disclosed |
| US-4685954-A | 3-acyl substituted of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A (IT) | 1987-08-11 | — | — | US | disclosed |
| US-4655818-A | 3-acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | MONTEDISON S.P.A. (IT) | 1987-04-07 | — | — | US | disclosed |
| EP-0207690-A1 | N-Substituted glutamic acid derivative and process for production and use thereof | SUNTORY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |
| EP-0090312-A2 | 3-Acyl substituted derivatives of 2- or 4-thiazolidine-carboxylic acid having a phyto growth regulating and biostimulating action | Montedison S.p.A. (IT) | 1983-10-05 | — | — | EP | disclosed |
| US-4314845-A | N4 -Phenoxyalkanoylsulfanilamides and herbicidal composition containing the same | SHIONOGI & CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380322-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | CYP1A2 1236/4885CYP2C9 1176/4885HIF1A 2059/4885 |
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | CYP1A2 1195/4885CYP2C9 966/4885HIF1A 1455/4885 |
| US-12116351-B2 | P2X4 receptor antagonist | P2RX7, P2RX1, P2RX2 | CYP1A2 1236/4885CYP2C9 1176/4885HIF1A 2059/4885 |
| US-20200223806-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | CYP1A2 1236/4885CYP2C9 1176/4885HIF1A 2059/4885 |
| US-11434207-B2 | P2X4 receptor antagonist | P2RX7, P2RX1, P2RX2 | CYP1A2 1236/4885CYP2C9 1176/4885HIF1A 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.