SCHEMBL1831224

SCHEMBL1831224

Cc1cc(Cl)ccc1OCC(=O)S

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.62
▸ CYP2C9 P11712 2/20 0.62
▸ HIF1A Q16665 1/20 0.62
▸ LMNA P02545 5/20 0.59
▸ SMN1; SMN2 Q16637 5/20 0.59
▸ HPGD P15428 2/20 0.59
▸ TSHR P16473 2/20 0.59
▸ MEN1 O00255 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ GAA P10253 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ MAPT P10636 3/20 0.58
▸ KDM4E B2RXH2 2/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ KCNH2 Q12809 1/20 0.58
▸ TP53 P04637 2/20 0.56
▸ ESR1 P03372 1/20 0.56
▸ POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metaxon SCHEMBL117877 0.85 TDP1 (0.70) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
SCHEMBL1195318 0.85 CYP1A2 (0.64) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
SCHEMBL8605798 0.85 CYP1A2 (0.64) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
SCHEMBL11640730 0.85 CYP1A2 (0.64) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
Metaxon SCHEMBL3533162 0.83 TDP1 (0.68) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
SCHEMBL11872902 0.83 MEN1 (0.68) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
Metaxon SCHEMBL28800416 0.83 TDP1 (0.68) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
Metaxon SCHEMBL27616565 0.83 TDP1 (0.68) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
SCHEMBL10734762 0.83 MEN1 (0.63) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2
Metaxon SCHEMBL27765431 0.83 TDP1 (0.68) CYP1A2CYP2C9HIF1ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390348-B1 DENDRIMER AND FORMULATIONS THEREOF LOVELAND PRODUCTS INC (US) 2024-04-17 — — EP claimed
US-20180370900-A1 DENDRIMER AND FORMULATIONS THEREOF STARPHARMA PTY LTD. (AU) 2018-12-27 — — US claimed
EP-3390348-A1 DENDRIMER AND FORMULATIONS THEREOF Priostar Pty Ltd (AU) 2018-10-24 — — EP claimed
WO-2017100856-A1 DENDRIMER AND FORMULATIONS THEREOF STARPHARMA PTY LTD (AU) 2017-06-22 — — WO claimed
US-20100016160-A1 HERBICIDAL COMPOSITIONS ISAGRO S.P.A. (IT) 2010-01-21 — — US claimed
WO-1998058545-A1 HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-30 — — WO claimed
WO-1989004607-A1 HERBICIDE COMPOSITION CONTAINING AT LEAST TWO ACTIVE AGENTS MTA Növényvédelmi Kutatóintézete (HU) 1989-06-01 — — WO claimed
JP-62209002-A — — None — — JP disclosed
JP-57193407-A — — None — — JP disclosed
JP-58189102-A — — None — — JP disclosed
EP-3390348-B1 DENDRIMER AND FORMULATIONS THEREOF LOVELAND PRODUCTS INC (US) 2024-04-17 — — EP disclosed
US-20230079931-A1 MICROFIBRILLATED CELLULOSE AS RHEOLOGY MODIFIER IN HIGH IONIC STRENGTH AGRICULTURAL FORMULATIONS AMVAC CHEMICAL CORP (US) 2023-03-16 — — US disclosed
US-11358905-B2 Microfibrillated cellulose as rheology modifier in high ionic strength agricultural formulations AMVAC CHEMICAL CORPORATION (US) 2022-06-14 — — US disclosed
JP-S62209002-A HERBICIDE FOR BARLEY FIELD HOKKO CHEM IND CO LTD 1987-09-14 — — JP disclosed
EP-0231765-A1 Use of membrane modulators and products comprising such membrane modulators A. Nattermann & Cie. GmbH (DE) 1987-08-12 — — EP disclosed
WO-1987004048-A1 USE OF MEMBRANE MODULATORS AND PRODUCTS COMPRISING SUCH MEMBRANE MODULATORS A. NATTERMANN & CIE GMBH (DE) 1987-07-16 — — WO disclosed
US-4447259-A 2-(Substituted phenoxy)propionic acid derivatives and their uses for herbicidal purposes HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1984-05-08 — — US disclosed
US-4426220-A Diphenyl ethers, their preparation and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1984-01-17 — — US disclosed
JP-S58189102-A FRUIT THINNING AGENT HOKKO CHEM IND CO LTD 1983-11-04 — — JP disclosed
JP-S57193407-A HERBICIDE FOR PADDY FIELD ZENKOKU NOGYO KYODO KUMIAI RENGOKAI 1982-11-27 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016160-A1 HERBICIDAL COMPOSITIONS DDT, AOX1, AS3MT CYP1A2 197/4885CYP2C9 170/4885HIF1A 4275/4885
US-20180370900-A1 DENDRIMER AND FORMULATIONS THEREOF DDT, PDCD2L, DNM2 CYP1A2 486/4885CYP2C9 958/4885HIF1A 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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