Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812381 | 1.00 | MEN1 (0.68) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10735111 | 0.90 | MEN1 (0.81) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL9779306 | 0.89 | SRD5A2 (0.56) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL29375096 | 0.88 | MEN1 (0.78) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL93420 | 0.88 | MEN1 (0.78) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10354488 | 0.86 | MEN1 (0.75) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL11232329 | 0.85 | MEN1 (0.62) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10937456 | 0.85 | CES2 (0.57) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2128469 | 0.83 | MEN1 (0.76) | MEN1KMT2AUSP2GAAKEAP1 | |
| 2,4-Dihydroxybenzophenone SCHEMBL19812527 | 0.82 | MEN1 (0.73) | MEN1KMT2AUSP2GAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362276-A1 | Small Molecule Inhibitors of Viral Replication | THE TRUSTEES OF PRINCETON UNIVERSITY | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362276-A1 | Small Molecule Inhibitors of Viral Replication | HSPH1, HSP90AB1, HSP90AA1 | MEN1 4192/4885KMT2A 3931/4885USP2 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.