Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735401 | 1.00 | LMNA (0.67) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL11268629 | 0.99 | LMNA (0.66) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL10983818 | 0.92 | TDP1 (0.57) | LMNATDP1HSD17B10L3MBTL1NR1I2 | |
| SCHEMBL10983814 | 0.92 | TDP1 (0.57) | LMNATDP1HSD17B10L3MBTL1NR1I2 | |
| SCHEMBL11183173 | 0.89 | TDP1 (0.68) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL11183181 | 0.89 | TDP1 (0.68) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL8770984 | 0.89 | TDP1 (0.55) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL8770998 | 0.89 | TDP1 (0.55) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL11181090 | 0.87 | TDP1 (0.67) | LMNATDP1HSD17B10L3MBTL1SLC22A6 | |
| SCHEMBL11181096 | 0.87 | TDP1 (0.67) | LMNATDP1HSD17B10L3MBTL1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379924-A | Cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-12 | — | — | US | claimed |
| EP-0221719-A2 | Novel cephalosporin derivatives, processes for their preparation and pharmaceutical compositions containing them | BIOGAL GYOGYSZERGYAR (HU) | 1987-05-13 | — | — | EP | disclosed |