Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770984 | 1.00 | TDP1 (0.55) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL8771048 | 0.92 | TDP1 (0.48) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL6542273 | 0.89 | TDP1 (0.55) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL10735409 | 0.89 | LMNA (0.67) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL10735401 | 0.89 | LMNA (0.67) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL11268629 | 0.88 | LMNA (0.66) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL8771238 | 0.87 | TDP1 (0.55) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL8771242 | 0.87 | TDP1 (0.55) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL8771053 | 0.87 | TDP1 (0.45) | TDP1LMNAHSD17B10L3MBTL1MAPT | |
| SCHEMBL8771017 | 0.87 | TDP1 (0.53) | TDP1LMNAHSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796263-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017850-A1 | CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-13 | — | — | WO | disclosed |