Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695215 | 0.78 | GRM5 (0.36) | MEN1POLBKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17432901 | 0.78 | MEN1 (0.35) | MEN1POLBKMT2ALMNAHTT | |
| SCHEMBL1487932 | 0.73 | CCR4 (0.40) | MEN1KMT2AHTTCCR4JAK3 | |
| SCHEMBL2608902 | 0.69 | S1PR4 (0.49) | TARBP2CHRM1TLR8 | |
| SCHEMBL17662595 | 0.69 | TSHR (0.36) | MEN1POLBKMT2ALMNAHTT | |
| SCHEMBL19121798 | 0.69 | MEN1 (0.49) | MEN1POLBKMT2ALMNAHTT | |
| SCHEMBL17248008 | 0.69 | NOS3 (0.41) | MEN1POLBKMT2ALMNAHTT | |
| SCHEMBL3458106 | 0.68 | KDM4E (0.44) | ABL1JAK3 | |
| SCHEMBL29364587 | 0.68 | KDM4E (0.44) | ABL1JAK3 | |
| SCHEMBL12301390 | 0.68 | GABRP (0.41) | MEN1POLBKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687848-A | CYCLIZING ALPHA-IMINODIACETONITRILES | BASF AKTIENGESELLSCHAFT (DE) | 1987-08-18 | — | — | US | disclosed |
| US-4560756-A | 2-Aminopyrazines and the preparation of 2-aminopyrazines and pyrazines | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| EP-0111717-A2 | 2-Aminopyrazine and process for the preparation of 2-aminopyrazines and pyrazines | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |