Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736721 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL11440259 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL11265608 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP2C9TSHRALOX15 | |
| SCHEMBL11265612 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP2C9TSHRALOX15 | |
| SCHEMBL10941446 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL10737430 | 0.81 | TSHR (0.33) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL10737435 | 0.81 | TSHR (0.33) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL11786885 | 0.79 | CYP2C9 (0.44) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 | |
| SCHEMBL11329037 | 0.79 | MAPT (0.44) | MAPTALOX12CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL8570905 | 0.79 | CYP2C9 (0.44) | ALDH1A1MAPTALOX12CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698337-A | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0095029-B1 | 5-THIO-TETRAZOL COMPOUNDS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4598147-A | THIAZOLE INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4582908-A | CHEMICAL INTERMEDIATES OF CEPHALOSPORIN DERIVATIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| EP-0049539-B1 | THIAZOLE DERIVATIVES FOR PREPARING CEPHEM COMPOUNDS AND PROCESSES FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-16 | — | — | EP | disclosed |
| EP-0029998-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |
| US-4493834-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| US-4420477-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0095029-A1 | 5-Thio-tetrazol compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-30 | — | — | EP | disclosed |
| US-4372952-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0049539-A1 | Thiazole derivatives for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-14 | — | — | EP | disclosed |
| US-RE30752-E | CHEMICAL REACTANT FOR PROTECTING AMINO OR IMINO GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| US-4284631-A | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0029998-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-10 | — | — | EP | disclosed |
| EP-0007633-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |
| US-4010178-A | Carbonic acid esters, and the preparation thereof and their use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3976635-A | Novel esterifying agents, and their production and use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-24 | — | — | US | disclosed |