Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329039 | 1.00 | MAPT (0.44) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL6969365 | 0.81 | — | — | |
| SCHEMBL9429335 | 0.81 | — | — | |
| SCHEMBL8569989 | 0.81 | — | — | |
| SCHEMBL10736721 | 0.79 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL11440259 | 0.79 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL10736729 | 0.79 | ALDH1A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL10737435 | 0.79 | TSHR (0.33) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL10737430 | 0.79 | TSHR (0.33) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 | |
| SCHEMBL11327513 | 0.77 | ALDH1A1 (0.44) | MAPTCYP1A2CYP3A4CYP2C9ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30752-E | CHEMICAL REACTANT FOR PROTECTING AMINO OR IMINO GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-29 | — | — | US | disclosed |
| US-4010178-A | Carbonic acid esters, and the preparation thereof and their use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3976635-A | Novel esterifying agents, and their production and use | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-24 | — | — | US | disclosed |