Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435089 | 0.78 | LMNA (0.49) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL30350713 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL15485106 | 0.77 | LMNA (0.51) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL8897383 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL18536181 | 0.77 | ALDH1A1 (0.49) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL29963948 | 0.77 | LMNA (0.51) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL569823 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL10610789 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL16127631 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E | |
| SCHEMBL8122140 | 0.77 | LMNA (0.48) | PKMNPSR1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647677-A | Process for preparing 2,3-dihydro-7-aminobenzofurans | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-03-03 | — | — | US | claimed |
| JP-61033183-A | — | — | None | — | — | JP | disclosed |
| EP-0236940-A2 | Alpha-heterocycle substituted tolunitriles | CIBA-GEIGY AG (CH) | 1987-09-16 | — | — | EP | disclosed |
| US-4647677-A | Process for preparing 2,3-dihydro-7-aminobenzofurans | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4594438-A | Dehydrohalogenation heating of 2,2,6-tri-halo-6-(1-halisobutyl)cyclohexanone | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| JP-S6133183-A | PREPARATION OF 2,3-DIHYDRO-7-AMINOBENZOFURAN | MITSUBISHI CHEM IND LTD | 1986-02-17 | — | — | JP | disclosed |
| EP-0090976-B1 | 2,2-DIHALO-6-HALO-6(1-HALOISOBUTYL)CYCLOHEXANONE | MITSUBISHI KASEI CORPORATION (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4499306-A | HALOGENATION OF 2-ISOBUTYLIDENE CYCLOHEXANONE IN PRESENCE OF CATALST | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0090976-A2 | 2,2-Dihalo-6-halo-6(1-haloisobutyl)cyclohexanone | MITSUBISHI KASEI CORPORATION (JP) | 1983-10-12 | — | — | EP | disclosed |