Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661511 | 0.84 | FFAR4 (0.43) | NR1H4PPARDNPC1RAB9AFFAR1 | |
| SCHEMBL10661416 | 0.84 | ALDH1A1 (0.50) | NR1H4PPARDALOX15MAPTPOLB | |
| SCHEMBL10730091 | 0.82 | NPC1 (0.38) | NPC1RAB9AMAPTTP53GPBAR1 | |
| SCHEMBL10735499 | 0.81 | NPC1 (0.38) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL10655912 | 0.81 | KDM4E (0.45) | NR1H4PPARDALOX15FFAR1POLB | |
| SCHEMBL10513064 | 0.81 | MAOB (0.40) | NPC1RAB9AMAPTTP53 | |
| SCHEMBL11258956 | 0.80 | PTGDR2 (0.42) | NR1H4PPARDNPC1RAB9AFFAR1 | |
| SCHEMBL10658733 | 0.79 | NPC1 (0.44) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL10655898 | 0.76 | KMT2A (0.38) | NR1H4PPARDNPC1RAB9AFFAR1 | |
| SCHEMBL10657153 | 0.76 | HIF1A (0.42) | NR1H4PPARDFFAR1PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | claimed |