Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661511 | 0.85 | FFAR4 (0.43) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL4035353 | 0.84 | FFAR4 (0.44) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL10655898 | 0.83 | KMT2A (0.38) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL10657153 | 0.80 | HIF1A (0.42) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL10737896 | 0.80 | NR1H4 (0.44) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL10655912 | 0.79 | KDM4E (0.45) | PTGDR2FFAR1PPARDNR1H4TDP1 | |
| SCHEMBL10663597 | 0.77 | PPARG (0.45) | PTGDR2FFAR1PPARDTDP1POLB | |
| SCHEMBL10659132 | 0.77 | HIF1A (0.41) | PTGDR2FFAR1PPARDNR1H4GPBAR1 | |
| SCHEMBL11560907 | 0.76 | PTGS1 (0.43) | GPBAR1TP53MAPTNPC1RAB9A | |
| SCHEMBL10661581 | 0.76 | FFAR4 (0.41) | PTGDR2FFAR1PPARDPPARGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002666-B1 | 1,2-BENZISOXAZOLYLOXY (OR THIO) ACETIC ACIDS AND RELATED COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-17 | — | — | EP | disclosed |