Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389088 | 0.80 | KMT2A (0.50) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL11170072 | 0.80 | KMT2A (0.40) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL10744737 | 0.75 | MEN1 (0.59) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL9391100 | 0.75 | KMT2A (0.47) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL9823847 | 0.75 | KMT2A (0.50) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL10745366 | 0.74 | MEN1 (0.39) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL6947959 | 0.73 | MEN1 (0.46) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL10742990 | 0.73 | MEN1 (0.38) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL10734466 | 0.73 | KMT2A (0.78) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL11163372 | 0.72 | POLB (0.76) | KMT2AMEN1HSP90AA1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4715887-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0032200-B1 | SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |