Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391100 | 0.86 | KMT2A (0.47) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL6947959 | 0.84 | MEN1 (0.46) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL10333795 | 0.83 | POLB (0.47) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL9270006 | 0.82 | KMT2A (0.49) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL10334009 | 0.82 | MEN1 (0.46) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL11369449 | 0.78 | KMT2A (0.79) | KMT2AMEN1HSP90AA1MAPTPOLB | |
| SCHEMBL10765937 | 0.77 | MEN1 (0.65) | KMT2AMEN1HSP90AA1TRPA1MAPT | |
| SCHEMBL10333724 | 0.76 | MEN1 (0.46) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL9824010 | 0.76 | MEN1 (0.46) | KMT2AMEN1HSP90AA1MAPTPOLB | |
| SCHEMBL10737985 | 0.75 | KMT2A (0.42) | KMT2AMEN1HSP90AA1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301393-B1 | 1,4-DISUBSTITUTED 1-AZOLYL-3,3-DYMETHYLBUTANE DERIVATIVES | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4968712-A | PHYTOPATHOGENS, AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0301393-A1 | 1,4-Disubstituted 1-azolyl-3,3-dymethylbutane derivatives | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |