Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823847 | 0.86 | KMT2A (0.50) | KMT2AMEN1TRPA1MAPTCYP19A1 | |
| SCHEMBL6947959 | 0.85 | MEN1 (0.46) | KMT2AMEN1TRPA1MAPTCYP19A1 | |
| SCHEMBL10334009 | 0.83 | MEN1 (0.46) | KMT2AMEN1TRPA1MAPTHSP90AA1 | |
| SCHEMBL10333795 | 0.82 | POLB (0.47) | KMT2AMEN1TRPA1MAPTCYP19A1 | |
| SCHEMBL9388155 | 0.78 | MAPT (0.44) | KMT2AMEN1MAPTCYP19A1HSP90AA1 | |
| SCHEMBL10333724 | 0.78 | MEN1 (0.46) | KMT2AMEN1HSP90AA1POLBTDP1 | |
| SCHEMBL9824010 | 0.78 | MEN1 (0.46) | KMT2AMEN1MAPTCYP19A1HSP90AA1 | |
| SCHEMBL10737985 | 0.75 | KMT2A (0.42) | KMT2AMEN1MAPTCYP19A1HSP90AA1 | |
| SCHEMBL10564644 | 0.74 | CYP19A1 (0.46) | CYP19A1HSP90AA1HDAC1HDAC8HDAC6 | |
| SCHEMBL10765937 | 0.74 | MEN1 (0.65) | KMT2AMEN1TRPA1MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001418-A1 | TRIAZOLYLBUTANE DERIVATIVES WITH A FUNGICIDAL ACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-20 | — | — | WO | disclosed |