Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407689 | 0.88 | SMN1; SMN2 (0.52) | TSHRCASP1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11298759 | 0.73 | CYP3A4 (0.48) | TSHRSMN1; SMN2ALDH1A1HPGDHIF1A | |
| SCHEMBL13816918 | 0.71 | ITGB2 (0.46) | TSHRALDH1A1HPGDHIF1AMEN1 | |
| SCHEMBL13816982 | 0.69 | CCR2 (0.36) | SMN1; SMN2ALDH1A1HPGDHIF1AMEN1 | |
| SCHEMBL27028671 | 0.68 | PDE7A (0.34) | TSHRSMN1; SMN2ALDH1A1HPGDHIF1A | |
| SCHEMBL10967073 | 0.68 | CYP3A4 (0.33) | ALDH1A1HPGDHIF1AMEN1KMT2A | |
| SCHEMBL10672960 | 0.68 | MAPT (0.43) | TSHRCASP1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10541315 | 0.66 | ALDH1A1 (0.68) | TSHRCASP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9692043 | 0.66 | ALDH1A1 (0.50) | TSHRCASP1SMN1; SMN2ALDH1A1HIF1A | |
| SCHEMBL8769572 | 0.66 | TSHR (0.45) | TSHRCASP1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673740-A | Preparation of substituted 2-phenyl-4H-3,1-benzoxazin-4-ones | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | US | disclosed |