Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793890 | 0.81 | DAO (0.43) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL2793886 | 0.81 | DAO (0.43) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL5367772 | 0.79 | DAO (0.52) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL5367777 | 0.79 | DAO (0.52) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL19987844 | 0.77 | DAO (0.64) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL6361220 | 0.76 | L3MBTL1 (0.49) | ALDH1A1PKMPOLBGAAMAPT | |
| SCHEMBL70493 | 0.74 | DAO (0.67) | DAOALDH1A1PKMPOLBLIG1 | |
| SCHEMBL1303016 | 0.74 | NPSR1 (0.60) | DAOALDH1A1PKMLIG1L3MBTL1 | |
| SCHEMBL10731718 | 0.74 | LMNA (0.44) | ALDH1A1POLBGAAMAPTL3MBTL1 | |
| SCHEMBL593258 | 0.73 | DAO (0.60) | DAOALDH1A1PKMPOLBLIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |