SCHEMBL10740372

SCHEMBL10740372

CC(C)CSc1cccc(O)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.47
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
APLNR P35414 1/20 0.38
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
HTR1A P08908 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR7 P34969 1/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 2/20 0.35
GAA P10253 1/20 0.35
ATM Q13315 1/20 0.35
ALPL P05186 1/20 0.34
PRNP P04156 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10463075 0.77 CNR2 (0.36) CNR2RAB9ASMN1; SMN2APLNRALDH1A1
SCHEMBL14152688 0.77 CNR2 (0.58) CNR2RAB9ASMN1; SMN2TSHRKMT2A
SCHEMBL10744794 0.76 HTR7 (0.42) APLNRHTR1ADRD2HTR2AHTR7
SCHEMBL9545606 0.76 HTR7 (0.35) HTR1ADRD2HTR2AHTR7
SCHEMBL14152637 0.74 CNR2 (0.40) CNR2RAB9ASMN1; SMN2HTR1ADRD2
SCHEMBL32665293 0.74
SCHEMBL2608954 0.69 KMT2A (0.58) RAB9ASMN1; SMN2TSHRMEN1HPGD
SCHEMBL19204573 0.69 NPC1 (0.51) RAB9ASMN1; SMN2TSHRHPGDALDH1A1
SCHEMBL1268799 0.69 ESR1 (0.41) CNR2RAB9ASMN1; SMN2TSHRMEN1
Ammonia Solution, Strong SCHEMBL7245354 0.68 KMT2A (0.57) RAB9ASMN1; SMN2TSHRMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652574-A Certain mono-, di- or tri-substituted pyridyl esters of alkane sulfonic acids having insecticidal, acaricidal and nematocidal properties NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-03-24 US disclosed
EP-0182603-A2 Alkanesulfonate derivatives useful as an insecticide, acaricide and nematicide NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-05-28 EP disclosed