SCHEMBL9545606

SCHEMBL9545606

C[Si](C)(C)CSc1cccc(O)n1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 6/20 0.35
HTR1A P08908 4/20 0.35
HTR2A P28223 4/20 0.35
DRD2 P14416 3/20 0.35
ESR1 P03372 1/20 0.31
AR P10275 1/20 0.31
HSD17B3 P37058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10740372 0.76 CNR2 (0.47) HTR7HTR1AHTR2ADRD2
SCHEMBL10744794 0.76 HTR7 (0.42) HTR7HTR1AHTR2ADRD2
SCHEMBL9545418 0.76 HTR1A (0.36) HTR7HTR1AHTR2ADRD2
SCHEMBL32665293 0.74
SCHEMBL433842 0.69 EHMT2 (0.52)
SCHEMBL128525 0.67
SCHEMBL19204573 0.66 NPC1 (0.51)
SCHEMBL8443558 0.65 P4HB (0.39) ESR1
SCHEMBL28270672 0.64 HTR7 (0.41) HTR7HTR1AHTR2ADRD2
Methane SCHEMBL7257614 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993021150-A2 ARTHROPODICIDAL ARYL SULFONATES DUNLENA PTY. LTD. (AU) 1993-10-28 WO disclosed