Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744806 | 0.87 | CYSLTR2 (0.57) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10800365 | 0.80 | CYSLTR2 (0.49) | CYP3A4PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL10796510 | 0.78 | CYP3A4 (0.45) | CYP3A4PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL10804163 | 0.77 | CYSLTR2 (0.49) | CYP3A4PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL16308872 | 0.76 | CYP4F2 (0.45) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL10794849 | 0.76 | CYP3A4 (0.55) | CYP3A4PPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL2987183 | 0.74 | CYP1A2 (0.58) | CYP2C9CYP2C19CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL10740501 | 0.74 | CYP3A4 (0.48) | CYP3A4PPARACYP2C9CYP2C19CYSLTR2 | |
| SCHEMBL14450970 | 0.73 | PTPN7 (0.56) | MAPTLMNAMEN1KMT2ATDP1 | |
| SCHEMBL10795393 | 0.73 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713486-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-12-15 | — | — | US | disclosed |
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | disclosed |