Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146577 | 0.77 | ALOX5 (0.51) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL28564819 | 0.77 | CYP3A4 (0.50) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10740470 | 0.76 | CYP3A4 (0.46) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4280713 | 0.74 | KCNH2 (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31544587 | 0.74 | KCNH2 (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13653518 | 0.74 | GABRP (0.38) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10794849 | 0.72 | CYP3A4 (0.55) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30912697 | 0.72 | CYP3A4 (0.59) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16058713 | 0.72 | GAA (0.59) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9345558 | 0.72 | CYP4F2 (0.50) | CYP4F2CYP4A11SMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457693-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-29 | — | — | US | disclosed |
| US-20190031688-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-01-31 | — | — | US | disclosed |
| US-10183957-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180201627-A9 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-07-19 | — | — | US | disclosed |
| US-20180201627-A9 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-07-19 | — | — | US | disclosed |
| US-20170037062-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-09 | — | — | US | disclosed |
| US-20170037062-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-09 | — | — | US | disclosed |
| US-9512147-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512147-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
| US-9238661-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-19 | — | — | US | disclosed |
| US-9238661-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-19 | — | — | US | disclosed |
| US-20140371444-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION | 2014-12-18 | — | — | US | disclosed |
| US-20140371444-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-20180201627-A9 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-10457693-B2 | Organoboron compounds and methods of making organoboron compounds | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-20140371444-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-20170037062-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-10183957-B2 | Organoboron compounds and methods of making organoboron compounds | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
| US-20190031688-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | CYP4F2 233/4885CYP4A11 371/4885SMN1; SMN2 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.