Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745835 | 0.87 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL10795247 | 0.84 | CYSLTR2 (0.65) | CYP3A4CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL10743657 | 0.84 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL27550548 | 0.82 | PTPN7 (0.58) | PPARGPPARATDP1KDM4EMAPT | |
| SCHEMBL12820360 | 0.82 | ALDH1A1 (0.57) | CYP3A4CYP2C9CYP2C19PPARGPPARA | |
| SCHEMBL6371432 | 0.82 | KCNH2 (0.58) | CYP3A4CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL8411340 | 0.78 | PTPN7 (0.63) | TDP1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL3966280 | 0.78 | PTPN7 (0.63) | TDP1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL10403786 | 0.78 | PTPN7 (0.63) | TDP1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL3129143 | 0.78 | PTPN7 (0.63) | TDP1KDM4EMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |