Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IGSF11 | Q5DX21 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736120 | 0.96 | TDP1 (0.52) | TDP1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10737433 | 0.81 | TDP1 (0.64) | TDP1SMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL10739940 | 0.81 | TDP1 (0.64) | TDP1SMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL10735516 | 0.80 | RORA (0.42) | TDP1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10740846 | 0.76 | ATM (0.51) | TDP1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10735119 | 0.76 | TDP1 (0.57) | TDP1SMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL10739938 | 0.76 | TDP1 (0.57) | TDP1SMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL10743331 | 0.74 | ATM (0.49) | TDP1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL18029436 | 0.74 | TDP1 (0.63) | TDP1SMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL14259780 | 0.71 | TSHR (0.64) | TDP1SMN1; SMN2NPSR1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |