Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737433 | 0.95 | TDP1 (0.64) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10741313 | 0.88 | NPSR1 (0.55) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10735119 | 0.85 | TDP1 (0.57) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10742041 | 0.85 | SMN1; SMN2 (0.44) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL18029436 | 0.83 | TDP1 (0.63) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10739940 | 0.81 | TDP1 (0.64) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10741199 | 0.80 | USP2 (0.57) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10736120 | 0.80 | TDP1 (0.52) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10740921 | 0.76 | TDP1 (0.58) | TDP1SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL10739963 | 0.75 | ALDH1A1 (0.60) | TDP1SMN1; SMN2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |