Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747007 | 0.90 | METAP2 (0.38) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10747439 | 0.90 | METAP2 (0.40) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL5916772 | 0.83 | METAP2 (0.54) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10744770 | 0.77 | KDM4E (0.44) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10747507 | 0.75 | METAP2 (0.37) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10748639 | 0.74 | METAP2 (0.37) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10501920 | 0.74 | METAP2 (0.40) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10746982 | 0.73 | NCF1 (0.50) | HTTLMNAMAPTKMT2AMPI | |
| SCHEMBL10749031 | 0.73 | METAP2 (0.38) | HTTMETAP2LMNAMAPTKMT2A | |
| SCHEMBL10746662 | 0.72 | METAP2 (0.38) | HTTMETAP2LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |