Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084720 | 0.81 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18415626 | 0.78 | KIF11 (0.47) | MEN1KMT2AKDM4EHSP90AA1HSD17B10 | |
| SCHEMBL31563113 | 0.77 | ATM (0.42) | ATMKEAP1NFE2L2MEN1HCRTR1 | |
| SCHEMBL8140534 | 0.76 | ATM (0.53) | ATMMEN1HCRTR1KMT2AKDM4E | |
| SCHEMBL7489417 | 0.76 | HPGD (0.61) | ATMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL15564817 | 0.75 | NQO2 (0.61) | ATMMEN1HCRTR1KMT2AKDM4E | |
| SCHEMBL31563337 | 0.74 | KDM4E (0.41) | ATMKEAP1NFE2L2MEN1HCRTR1 | |
| SCHEMBL13925420 | 0.74 | ATM (0.67) | ATMMEN1HCRTR1KMT2AKDM4E | |
| SCHEMBL27344753 | 0.73 | MAPT (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8040679 | 0.73 | ALDH1A1 (0.56) | MEN1HCRTR1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |