SCHEMBL1074347

SCHEMBL1074347

Cc1cc(C)c(OS(C)(=O)=O)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CYP1A2 P05177 1/20 0.40
ALPL P05186 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
RAPGEF4 Q8WZA2 7/20 0.38
CA9 Q16790 1/20 0.36
FFAR4 Q5NUL3 3/20 0.35
F2 P00734 2/20 0.35
PRSS1 P07477 2/20 0.35
PRSS2 P07478 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12000723 0.82 CYP1A2 (0.38) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL
SCHEMBL3843136 0.80 TSHR (0.37) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL
SCHEMBL3838558 0.80 CYP1A2 (0.37) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL
SCHEMBL7608122 0.80 FFAR4 (0.44) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL
SCHEMBL4876000 0.79 CA2 (0.48) CA1CA2MMP1MMP2MMP9
SCHEMBL14015374 0.79 CA1 (0.42) TSHRCA1CA2MMP1MMP2
SCHEMBL16140138 0.79 RAPGEF4 (0.41) CA1CA2MMP1MMP2MMP9
SCHEMBL9849488 0.79 FFAR4 (0.39) TSHRCA1CA2MMP1MMP2
SCHEMBL20614633 0.79 FABP3 (0.37) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL
SCHEMBL4966715 0.79 SRC (0.50) CSNK2A2CSNK2BCSNK2A1CYP1A2ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-220179462-U Slicing device for processing of photovoltaic Metinib mesylate tablets 江苏艾力斯生物医药有限公司 2023-12-15 CN claimed
CN-220163312-U Tablet pressing device for producing photovoltaic Meitinib mesylate tablets 江苏艾力斯生物医药有限公司 2023-12-12 CN claimed
US-20110077360-A1 PROCESS FOR REACTING CHEMICAL COMPOUNDS IN THE PRESENCE OF CATALYST SYSTEMS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-31 US claimed
WO-2011023788-A1 PROCESS FOR THE PREPARATION OF HYDROGENATED NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2011-03-03 WO claimed
EP-2289620-A1 Process for the preparation of hydrogenated nitrile rubber LANXESS Deutschland GmbH (DE) 2011-03-02 EP claimed
US-7875683-B2 subjecting them to a metathesis reaction in the presence of specific rhodium- or ruthenium-containing catalyst; increase in the reaction rate and the setting of lower molecular weights of the degraded nitrite rubber LANXESS DEUTSCHLAND GMBH (DE) 2011-01-25 US claimed
CN-110650959-B Therapeutic compounds and compositions and methods of use thereof 豪夫迈·罗氏有限公司 2023-04-18 CN disclosed
CN-111683950-A AhR modulators 伊迪亚生物科学有限公司 2020-09-18 CN disclosed
US-8283508-B2 Method for producing aromatic compound UBE INDUSTRIES, LTD. (JP) 2012-10-09 US disclosed
US-20110230694-A1 METHOD FOR PRODUCING AROMATIC COMPOUND UBE INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
US-20110077360-A1 PROCESS FOR REACTING CHEMICAL COMPOUNDS IN THE PRESENCE OF CATALYST SYSTEMS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-31 US disclosed
WO-2011023674-A1 RUTHENIUM BASED CATALYSTS FOR THE METATHESIS OF NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-03 WO disclosed
WO-2011023788-A1 PROCESS FOR THE PREPARATION OF HYDROGENATED NITRILE RUBBER LANXESS DEUTSCHLAND GMBH (DE) 2011-03-03 WO disclosed
EP-2289620-A1 Process for the preparation of hydrogenated nitrile rubber LANXESS Deutschland GmbH (DE) 2011-03-02 EP disclosed
EP-2289621-A1 Process for the preparation of low molecular weight hydrogenated nitrile rubber LANXESS Deutschland GmbH (DE) 2011-03-02 EP disclosed
EP-2289622-A1 Ruthenium based catalysts for the metathesis of nitrile rubbers LANXESS Deutschland GmbH (DE) 2011-03-02 EP disclosed
US-7875683-B2 subjecting them to a metathesis reaction in the presence of specific rhodium- or ruthenium-containing catalyst; increase in the reaction rate and the setting of lower molecular weights of the degraded nitrite rubber LANXESS DEUTSCHLAND GMBH (DE) 2011-01-25 US disclosed
CN-1720043-A Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INT (DE) 2006-01-11 CN disclosed