SCHEMBL1074445

SCHEMBL1074445

CCCCC/C(C#N)=C(/CCCCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.53
FNTB P49356 2/20 0.53
THRB P10828 1/20 0.53
PGGT1B P53609 1/20 0.53
AKR1B1 P15121 1/20 0.45
GPR84 Q9NQS5 7/20 0.43
PPARG P37231 7/20 0.43
PPARD Q03181 7/20 0.43
PPARA Q07869 7/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
PTPN1 P18031 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074447 1.00 FNTA (0.53) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL11910003 0.98 FNTA (0.56) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL11910002 0.98 FNTA (0.56) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL540775 0.89 FNTA (0.55) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL540774 0.89 FNTA (0.50) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL18606215 0.85 THRB (0.40) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL18606216 0.85 FNTA (0.44) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL540685 0.79 FNTA (0.56) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL540686 0.79 FNTA (0.61) FNTAFNTBTHRBPGGT1BAKR1B1
SCHEMBL183671 0.79 FNTA (0.71) FNTAFNTBTHRBPGGT1BAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2157134-B1 Films with improved characteristics BAYER MATERIALSCIENCE AG (DE) 2011-10-19 EP disclosed
EP-2133203-B1 Multi-layer optical film constructions with improved characteristics and use thereof BAYER MATERIALSCIENCE AG (DE) 2011-01-19 EP disclosed
EP-2157134-A1 Films with improved characteristics Bayer MaterialScience AG (DE) 2010-02-24 EP disclosed
EP-2157133-A1 Films with improved characteristics Bayer MaterialScience AG (DE) 2010-02-24 EP disclosed
EP-2133202-A1 Multi-layer optical film constructions with improved characteristics and use thereof Bayer MaterialScience AG (DE) 2009-12-16 EP disclosed
EP-2133203-A1 Multi-layer optical film constructions with improved characteristics and use thereof Bayer MaterialScience AG (DE) 2009-12-16 EP disclosed