SCHEMBL540775

SCHEMBL540775

CCCCCCC(C(=O)O)=C(C#N)CC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.55
FNTB P49356 2/20 0.55
THRB P10828 1/20 0.55
PGGT1B P53609 1/20 0.55
GPR84 Q9NQS5 7/20 0.45
PPARG P37231 7/20 0.45
PPARD Q03181 7/20 0.45
PPARA Q07869 7/20 0.45
HDAC11 Q96DB2 5/20 0.45
TSHR P16473 4/20 0.45
PTPN1 P18031 3/20 0.45
ALDH1A1 P00352 2/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18606216 0.93 FNTA (0.44) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL11910003 0.91 FNTA (0.56) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL11910002 0.91 FNTA (0.56) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL1074447 0.89 FNTA (0.53) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL1074445 0.89 FNTA (0.53) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL540774 0.86 FNTA (0.50) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL540686 0.80 FNTA (0.61) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL13121532 0.78 CES2 (0.42) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL183951 0.78 FNTA (0.75) FNTAFNTBTHRBPGGT1BGPR84
SCHEMBL1051704 0.78 FNTA (0.75) FNTAFNTBTHRBPGGT1BGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230138395-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE BIOSERGEN AS (NO) 2023-05-04 US disclosed
EP-4110305-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE Biosergen AS (NO) 2023-01-04 EP disclosed
EP-1647262-B2 Anhydrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair OREAL (FR) 2012-02-08 EP disclosed
EP-1647262-B1 Anhydrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair OREAL (FR) 2009-08-05 EP disclosed
EP-2065026-A1 Composition comprising, in an anhydrous cosmetically acceptable medium, electrophilic monomers and an acid, and its use for cosmetic treatment of hair L'Oreal (FR) 2009-06-03 EP disclosed
EP-1649898-A2 Dye composition comprising a pigment and at least one specific electrophilic monomer L'OREAL (FR) 2006-04-26 EP disclosed
EP-1649894-A2 Composition comprising electrophilic monomers and organic salts, use for treatment of keratinic materials L'OREAL (FR) 2006-04-26 EP disclosed
EP-1649895-A2 Oxidizing composition comprising at least one electrophilic monomer and an oxidant with exception of benzoquinone L'OREAL (FR) 2006-04-26 EP disclosed
EP-1649896-A2 Dye composition comprising a mixtrure of pigment and electophilic monomer L'OREAL (FR) 2006-04-26 EP disclosed
EP-1649897-A2 Dye composition comprising a pigment and at least an electrophilic monomer L'OREAL (FR) 2006-04-26 EP disclosed
EP-1647265-A1 Use for the cosmetic treatment of keratinous material of non sticky compositions based on electrophilic monomeres and non-silicon polymers L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647264-A1 use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a rigid coating L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647260-A1 use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a soft coating L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647259-A1 use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647258-A1 Hair care composition based on electrophilic monomers and lubricating solid micro or nano particles L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647263-A1 Double chamber aerosol device comprising electrophilic monomers and use for the cosmetic treatment of hair L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647261-A1 Composition for the treatment of keratinous material based on electrophilic monomers and salts L'OREAL (FR) 2006-04-19 EP disclosed
EP-1647262-A1 Anhyrous cosmetic composition comprising electrophilic monomers and acid, and use for cosmetic treatment of hair L'OREAL (FR) 2006-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230138395-A1 PHARMACEUTICAL COMPOSITIONS OF A THERAPEUTIC POLYENE MACROLIDE AND METHODS OF THEIR USE CEL, LIPA, HDAC6 FNTA 475/4885FNTB 908/4885THRB 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.