Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740889 | 0.89 | MAPT (0.49) | PPARDPPARAPPARGGAAMAPT | |
| SCHEMBL10746094 | 0.84 | FKBP1A (0.53) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| SCHEMBL11817237 | 0.84 | FFAR1 (0.47) | PPARDPPARAPPARGMAPTNPSR1 | |
| SCHEMBL11818931 | 0.84 | FKBP1A (0.50) | PPARDPPARAPPARGHPGDFKBP1A | |
| SCHEMBL11819040 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| SCHEMBL11825095 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| SCHEMBL11821280 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| SCHEMBL11821844 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| SCHEMBL11820125 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL11820558 | 0.83 | FKBP1A (0.52) | PPARDPPARAPPARGHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |