Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | PTPRG | P23470 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746094 | 0.88 | FKBP1A (0.53) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL11820125 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| Ammonia Solution, Strong SCHEMBL11820558 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL11819040 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL11825095 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL11821280 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL11821844 | 0.86 | FKBP1A (0.52) | FKBP1APTPRGPTPRCPPARDKDM4E | |
| SCHEMBL10744475 | 0.84 | PPARD (0.49) | FKBP1APPARDHPGDPPARGPPARA | |
| SCHEMBL11823732 | 0.83 | GFER (0.54) | FKBP1AALDH1A1HPGDLMNA | |
| SCHEMBL11818557 | 0.83 | FKBP1A (0.47) | FKBP1APTPRGPPARDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |