Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.66 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 13/20 | 0.46 |
| ▸ | MGMT | P16455 | 6/20 | 0.46 |
| ▸ | CDK1 | P06493 | 12/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 12/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Diaminopurine SCHEMBL13857840 | 0.88 | PDPK1 (0.79) | PDPK1GDADPP4CDK2MGMT | |
| Triphosphate SCHEMBL30196670 | 0.86 | PDPK1 (0.46) | PDPK1GDADPP4CDK2MGMT | |
| Triphosphate SCHEMBL502620 | 0.81 | PI4KA (0.65) | PDPK1GDACDK2 | |
| Triphosphate SCHEMBL29941501 | 0.81 | PI4KA (0.65) | PDPK1GDACDK2 | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.81 | PDPK1 (1.00) | PDPK1GDADPP4CDK2MGMT | |
| Triphosphate SCHEMBL27978070 | 0.81 | ADORA3 (0.51) | PDPK1GDACDK2MGMTCDK1 | |
| SCHEMBL7080816 | 0.80 | PDPK1 (0.49) | PDPK1GDADPP4CDK2MGMT | |
| Adenine SCHEMBL29843997 | 0.80 | PI4KA (0.63) | PDPK1GDACDK2 | |
| 2,6-Diaminopurine SCHEMBL8757979 | 0.79 | PDPK1 (0.96) | PDPK1GDADPP4CDK2MGMT | |
| 2,6-Diaminopurine SCHEMBL28206545 | 0.79 | PDPK1 (0.96) | PDPK1GDADPP4CDK2MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979492-B1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | PASTEUR INSTITUT (FR) | 2014-10-29 | — | — | EP | claimed |
| EP-1979492-B1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | PASTEUR INSTITUT (FR) | 2014-10-29 | — | — | EP | disclosed |
| US-8541206-B2 | Differential amplification of mutant nucleic acids by PCR in a mixture of nucleic acids | INSTITUT PASTEUR (FR) | 2013-09-24 | — | — | US | disclosed |
| US-20110003282-A1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2011-01-06 | — | — | US | disclosed |
| US-20100184017-A1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR | 2010-07-22 | — | — | US | disclosed |
| EP-1979492-A2 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007091125-A2 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2007-08-16 | — | — | WO | disclosed |
| US-20070154892-A1 | Differential amplification of mutant nucleic acids by PCR in a mixure of nucleic acids | INSTITUT PASTEUR (FR) | 2007-07-05 | — | — | US | disclosed |