SCHEMBL10744779

SCHEMBL10744779

Cc1cc2ccccc2c(S(=O)(=O)Cl)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.41
CYP2A6 P11509 3/20 0.41
TSHR P16473 1/20 0.38
CYP2D6 P10635 1/20 0.37
ALDH1A1 P00352 5/20 0.37
HPGD P15428 4/20 0.37
KDM4E B2RXH2 4/20 0.37
GAA P10253 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP3A4 P08684 1/20 0.36
XBP1 P17861 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437289 0.82 CYP2D6 (0.51) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
SCHEMBL8415193 0.82 CA2 (0.43) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
Hydrochloric Acid SCHEMBL27863421 0.81 CYP2D6 (0.50) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
SCHEMBL2426275 0.81 NR1I2 (0.41) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
Potassium Ion SCHEMBL7030033 0.81 CYP1A2 (0.40) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
Ammonia Solution, Strong SCHEMBL11422698 0.81 CYP2D6 (0.50) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
SCHEMBL2343292 0.81 L3MBTL1 (0.45) CYP1A2CYP2D6ALDH1A1HPGDKDM4E
Formaldehyde SCHEMBL3281234 0.79 CYP2D6 (0.49) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
Formaldehyde SCHEMBL2859235 0.78 NR1I2 (0.39) CYP1A2CYP2A6TSHRCYP2D6ALDH1A1
SCHEMBL2574159 0.78 CYP2A6 (0.50) CYP1A2CYP2A6TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4701565-A REACTING ALCOHOL WITH ORGANIC SULFONYL HALIDE TO FORM SULFONATE, REACTING SULFONATE WITH A PHENOL FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed