SCHEMBL10744915

SCHEMBL10744915

NC(=O)CCC(NC(=O)OCc1ccccc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APC P25054 3/20 0.59
CTSL P07711 2/20 0.51
KISS1R Q969F8 2/20 0.48
QRFPR Q96P65 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MME P08473 2/20 0.46
ECE1 P42892 2/20 0.46
TFPI P10646 1/20 0.45
CTSB P07858 1/20 0.45
CTSS P25774 1/20 0.45
CTSK P43235 1/20 0.45
KEAP1 Q14145 1/20 0.45
PSMB8 P28062 1/20 0.45
PSMB5 P28074 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10744918 1.00 APC (0.59) APCCTSLKISS1RQRFPRSMN1; SMN2
SCHEMBL10741001 1.00 APC (0.59) APCCTSLKISS1RQRFPRSMN1; SMN2
SCHEMBL10740994 1.00 APC (0.59) APCCTSLKISS1RQRFPRSMN1; SMN2
SCHEMBL10745790 0.86 CTSL (0.62) CTSLMMEECE1CTSBCTSS
SCHEMBL10745783 0.86 CTSL (0.62) CTSLMMEECE1CTSBCTSS
SCHEMBL10740146 0.86 APC (0.51) APCKISS1RQRFPRTFPI
SCHEMBL10740108 0.85 APC (0.48) APCCTSLSMN1; SMN2CTSSCTSK
SCHEMBL10742707 0.85 QRFPR (0.51) KISS1RQRFPR
SCHEMBL10742699 0.85 QRFPR (0.51) KISS1RQRFPR
SCHEMBL10746375 0.85 QRFPR (0.52) KISS1RQRFPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232435-A2 Serum thymic factor peptide analogs and a process for the preparation thereof SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1987-08-19 EP disclosed